| Date | Opponent | Result |
|---|---|---|
| Thursday, 11/18/21, 6:00PM | Scrimmage @Brownsburg | n/a |
| Wednesday, 11/24/21, 7:30PM | @Greenwood | W 67-35 (1-0) |
| Saturday, 11/27/21, 11:30AM | Franklin Central | L 56-65 (1-1) |
| Saturday, 12/4/21, 7:30PM | Bloomington North (CGBBL Night) | L 52-59 (1-2) |
| Friday, 12/10/21, 7:30PM | Pike (1972 Golden Anniversary Night) | L 54-66 (1-3) |
| Saturday, 12/11/21, 7:30PM | @Martinsville | W 79-46 (2-3) |
| Friday, 12/17/21, 7:30pm | Whiteland (Cheerleader Holiday Dance) | W 61-46 (3-3) |
| Saturday, 12/18/21, 7:30pm | @Avon | W 59-48 (4-3) |
| Wednesday, 12/22/21, 7:30pm | Perry Meridian (Grandparent's Night) | W 44-37 (5-3) |
| Friday, 1/7/22, 7:30PM | @Carmel | L 20-44 (5-4) |
| Saturday, 1/8/22, 7:30PM | Jennings County (Best Buddies Night) | W 71-48 (6-4) |
| Friday, 1/14/22, 7:30PM | Johnson County Tournament vs Franklin (@Indian Creek) | W 54-35 (7-4) |
| Saturday, 1/15/22, 7:00PM | Johnson County Tournament vs. Whiteland (@Indian Creek) | L 43-46 (7-5) |
| Friday, 1/21/22, 7:30PM | Ben Davis (Middle School Night) | L 43-44 (7-6) |
| Saturday, 1/22/22, 7:30pm | @Roncalli | W 50-37 (8-6) |
| Friday, 1/28/22, 7:30pm | @Lawrence North | L 53-69 (8-7) |
| Tuesday, 2/8/22, 7:30PM | @Zionsville | L 46-47 (8-8) |
| Friday, 2/11/22, 7:30PM | Lawrence Central (Pack the Vandy Night) | L 53-54 (8-9) |
| Tuesday, 2/15/22, 7:30PM | @Mooresville | L 55-57 (8-10) |
| Friday, 2/18/22, 7:30PM | North Central | W 54-40 (9-10) |
| Saturday, 2/19/2022 | Warren Central | W 53-45 (10-10) |
| Tuesday, 2/22/22, 7:30PM | Brownsburg (Senior Night) | L 46-53 (10-11) |
| Thursday, 2/24/22, 7:30PM | @Columbus North | L 37-40 (10-12) |
| Friday, 3/4/22, 7:30PM | Sectional Semifinals vs. Franklin Central (played @Greenwood) | W 60-52 (11-12) |
| Saturday, 3/5/22, 7:30PM | Sectional Finals vs. Franklin (played @Greenwood) | L 45-54 (11-13) |
