| Date | Opponent | Result |
|---|---|---|
| Tuesday, 11/23/21, 6:00PM | @Decatur Central | W 47-28 (1-0) |
| Wednesday, 11/24/21, 6:00PM | @Greenwood | W 47-38 (2-0) |
| Wednesday, 12/1/21, 6:00PM | Mooresville | W (3-0) |
| Saturday, 12/4/21, 6:00PM | Bloomington North | L 37-39 (3-1) |
| Wednesday, 12/8/21, 6:00PM | Bloomington South | W 44-28 (4-1) |
| Friday, 12/10/21, 6:00PM | Pike | L 53-51 (4-2) |
| Saturday, 12/17/21, 6:00PM | @Martinsville | W 49-35 (5-2) |
| Friday, 12/17/21, 6:00PM | Whiteland | W 51-46 (6-2) |
| Saturday, 12/18/21, 6:00PM | @Avon | L 39-48 (6-3) |
| Wednesday, 12/22/21, 6:00PM | Perry Meridian | W 49-14 (7-3) |
| Friday, 1/7/22, 6:00PM | @Carmel | W 46-39 (8-3) |
| Saturday, 1/8/22, 6:00PM | Jennings County | W 51-19 (9-3) |
| Thursday, 1/13/22, 6:00PM | North Central | W 50-37 (10-3) |
| Friday, 1/21/22, 6:00PM | Ben Davis | W 40-35 (11-3) |
| Saturday, 1/22/22, 6:00PM | @Roncalli | L 30-40 (11-4) |
| Wednesday, 1/26/22, 6:00PM | Lawrence Central | W 60-42 (12-4) |
| Friday, 1/28/22, 6:00PM | @Lawrence North | W 40-36 (13-4) |
| Tuesday, 2/8/22, 6:00PM | @Zionsville | L 46-49 (13-5) |
